On January 8, 2024, CorrectSequence Therapeutics Co., Ltd. (Correctseq), a  ShanghaiTech spinoff, using innovative transformer Base Editing (tBE) technology to help people with severe diseases, announced positive results of its base editing therapy for transfusion-dependent β-thalassemia, CS-101. As a collaboration with the First Affiliated Hospital of Guangxi Medical University, t...

Year 2023 marks the 10th anniversary of ShanghaiTech University. As a connection between the past and future, ShanghaiTech Innovation & Entrepreneurship Summit (techIES) serves to welcome the university’s further development in the new decade. On December 22, 2023, the Carnival Event of the 6th techIES was held in the Conference Center, marking a successful conclusion of this year’s summit a...

 The development of artificial intelligence relies, primarily, on deep neural networks, and the large-scale neural network language models like ChatGPT have posed great challenges to the electronic computing chips based on the von Neumann architecture. As a promising solution, optical computing can boost energy efficiency and reduce computation latency. In recent years, a large variety o...

Through a 100-million-year evolution and adaptation, the eutherian placentae has become one ofthe most morphologically variable organs. Besides the fetal-maternal exchange, recent studies in mouse models have demonstrated that developmental defects in placentae could exert pronounced effects on embryo growth and development, leading to the necessity for high-throughput screens on modulators for mo...

Hepatocellular carcinoma, a highly prevalent malignant tumor in China, accounts for nearly half of the newly diagnosed cases and deaths worldwide annually. Among liver cancer patients, 70-80% are diagnosed with tumor spread and metastasis, rendering them ineligible for surgical intervention. However, a comprehensive understanding of the molecular characteristics specific to metastatic liver cancer...

Associate Professor Zheng Jie’s lab in SIST has recently proposed an advanced artificial intelligence model named KR4SL. By integrating knowledge graphs and explainable graph neural networks, KR4SL has made strides in identifying anti-cancer drug targets based on synthetic lethality. This work has been formally published as a Proceedings paper in the top international bioinformatics conferen...

Stress granules (SGs) are membrane-less organelles that transiently arise in the cytoplasm in response to adverse environmental conditions. They form through liquid-liquid phase separation (LLPS). SGs are thought to regulate mRNA functions during stress and participate in cell-fate specification by orchestrating the depletion and release of cytosolic regulatory proteins. Much effort has been focus...

Visiting Assistant Professor Zhou Xinan in SPST is awarded the 2023 ICTP Prize, a prestigious international prize from the International Centre for Theoretical Physics (ICTP). Established in 1964 by Nobel Laureate Abdus Salam in Trieste Italy, ICTP is a renowned international scientific hub and a UNESCO-affiliated organization that is committed to promoting science in the underdeveloped world. The...

 The 2023 ShanghaiTech Annual Symposium on Biomedical Engineering (ASBME 2023) was held in the University Auditorium on November 11. The symposium aims to promote extensive exchanges about the latest academic achievements in biomedical engineering and to explore the future direction of the discipline and transfer prospects. Twelve well-known scholars from the field of biomedical eng...

On November 9, the AMR Conference co-sponsored by the journal Accounts of Materials Research (AMR) and ACS Publications came to a successful conclusion.  With the theme of “Materials for a Better Future”, this conference focused on the frontier hot topics and future directions of nano and porous materials research. The conference invited well-known domestic and foreign scholars in...

CorrectSequence Therapeutics (Correctseq), a biotechnology company incubated from ShanghaiTech using innovative base editing technology to help people with severe diseases, today announced that the company and the research teams from ShanghaiTech University, Wuhan University, Fudan University and Children’s Hospital of Fudan University published an article entitled “Base editing of the HBG ...

On November 24, the International Session on Biomed of the 6th ShanghaiTech Innovation and Entrepreneurship Summit (techIES) took place in the University Auditorium, adopting a hybrid format. Leaders from the Shanghai Clinical Research and Trial Center, Office of Tech Transfer, and Office of International Affairs (OIA) attended the event. Dr. Nie Yan, Deputy Director of OIA, delivered an opening s...

The Shanghai Clinical Research and Trial Center is a research-oriented hospital approved by the Shanghai Municipal Government and directly subordinate to the Shanghai Municipal Health Commission. It is being built and managed by ShanghaiTech University.  On September 30, 2022, the Center broke ground on the block next to the university campus in Zhangjiang. The construction currently underway...

Recently, Assistant Professor Wang Chundong’s research group in SIST independently discovered a covert channel based on the fsync function within computer storage and named it Sync+Sync. The result was published in an article entitled “Sync+Sync: A Covert Channel Built on fsync with Storage”, and was accepted by USENIX Security 2024, one of the top four international conferences in the field of...