Autophagy is a conserved eukaryotic cellular process that delivers protein aggregates, damaged organelles, and invaded pathogens to the lysosome for degradation. Reticulophagy is a specialized form of autophagy that selectively breaks down damaged or redundant endoplasmic reticulum (ER) using the autophagy-lysosome pathway, thus maintaining ER homeostasis and dynamic equilibrium. Reticulophagy rec...

Abiotic stresses such as drought, salinity, and extreme temperatures threaten global crop yields. For optimum crop productivity, plants must efficiently combat these stresses. Rapid accumulation of proline under stress is a key feature and primary defense strategy in plants. Arabidopsis thaliana pyrroline-5-carboxylate synthase (AtP5CS), involved in proline metabolism, serves as the rate...

Optical frequency comb, composed of discrete spectral lines, derives the name from its presenting a uniform and comb-like distribution of signals in the frequency domain. Frequency dimension has its significance as emphasized by Nobel laureate Arthur Schawlow’s quote, “Never measure anything but frequency”. The optical frequency comb significantly enhances the precision of freque...

On May 6, the International Society for Magnetic Resonance in Medicine (ISMRM) officially announced its list of ISMRM Fellows for 2024, with Professor Shen Dinggang, Founding Dean of the School of Biomedical Engineering at ShanghaiTech University, among those honored. Prior to this recognition, Professor Shen had been elected as a Fellow of the Institute of Electrical and Electronics Engineers (IE...

Led by Professor Liu Ji-Long in the School of Life Science and Technology, a research team has recently made strides in comprehending the structure and inhibition mechanisms of prokaryotic cytidine triphosphate (CTP) synthase, as detailed in the academic journal mLife in a paper entitled “Filamentation and inhibition of prokaryotic CTP synthase with ligands” on May ...

The testes are the site of sperm production and secretion of male hormones. Testicular aging not only leads to a decline in fertility but also significantly affects the quality of life for men. Late-onset hypogonadism (LOH) is a typical pathological change of testicular aging, characterized by testosterone deficiency and other related clinical symptoms. Prolonged testosterone deficiency can also c...

On the afternoon of April 12, Teng Jin-Guang, President of the Hong Kong Polytechnic University (PolyU), visited ShanghaiTech University. Jiang Mianheng, President of ShanghaiTech University, met with the delegation led by President Teng.President Jiang extended a warm welcome to the PolyU delegation at the meeting. Following the introduction of each university’s vision, mission and general infor...

Halide perovskite solar cells are currently deemed as the most promising third-generation photovoltaic technology, opening vast opportunities for transformative development in the solar cell industry. In recent years, the efficiency of halide perovskite cells has been constantly improved, however, there remains a gap compared to the theoretical limits. Therefore, enhancing the efficiency of perovs...

Under the guidance of Assistant Professor Feng Jicheng in the School of Physical Science and Technology (SPST), a research team has recently made a significant contribution to the fabrication of complex architectures at the nanoscale. Their findings, published in the journal Advanced Functional Materials in March and featured as the journal’s back cover, introduced an innovative 3D nano...

On the afternoon of March 13, a collaborative seminar, jointly organized by ShanghaiTech, Shanghai Clinical Research and Trial Center, and Swissnex in China, was convened at the Conference Center of ShanghaiTech University. The seminar, with the theme of “Future Hospitals: Research Institutes Meet Industry”, brought together eminent representatives from sectors of medicine, science, and industry...

Recently, Assistant Professor Mao Yijie in the School of Information Science and Technology (SIST), successfully joined the list of “100 Brilliant and Inspiring Women in 6G” in 2024. The list was announced by the community “Women in 6G™”, aiming to recognize 100 women who have made outstanding contributions in the field of 6G telecom around the world.“Women in 6G™” is an international o...

Microbubble cavitation-based focused ultrasound therapies can non-invasively open biological barriers temporarily, such as the blood-brain barrier and blood-tumor barrier. This emerging new type of therapy is undergoing a huge number of clinical investigations for drug delivery and for removing pathological tissues without opening the human body, and has great potential for the treatment of brain ...

Perovskite is currently the most promising new type of solar cell material. Perovskite-based ultra-efficient solar cells have been rated as one of the “Top 10 Breakthrough Technologies of 2024” by MIT Technology Review. The commonly used lead perovskite solar cells have achieved high photoelectric conversion efficiency, but they still have shortcomings in terms of environmental friendliness and ...

 In recent years, ShanghaiTech University has continued to deepen the reform in education and teaching, to pay significant attention to the improvement of undergraduate education quality, and has made new progress in curriculum building and textbook compilation. In 2023, four ShanghaiTech courses joined the list of “First-class undergraduate courses in universities in Shanghai”, five course...